Scientific Slide Deck Mode — Dr Idelphonse Ahogni, PhD

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01Scientific Presentation

Dr Idelphonse Bonaventure AHOGNI, PhD

Medical Entomologist · Malaria Program Manager · Senior Researcher at CREC Benin

Advanced expertise in operational evaluation of vector control interventions (LLINs, IRS), genomic surveillance of insecticide resistance (kdr, ace-1, CYP450), and high-level strategic advisory for public health programs across sub-Saharan Africa.

500+Citations
25+Q1/Q2 Publications
10+African Countries
12h-index
02Core Challenges

The Threat of Insecticide Resistance

Erosion of conventional pyrethroid efficacy across West Africa

In rural and peri-urban southern/central Benin, kdr L1014F mutation frequency exceeds 90% in Anopheles gambiae s.l., compounded by intense metabolic P450 cytochrome (CYP6P3) overexpression. Transitioning to next-generation dual-active tools is urgent.

> 90%Benin kdr frequency
2xPBO net residual life
100%WHO alignment
03Technological Innovations

Next-Generation Dual-Active LLINs

Clinical & entomological validation of Interceptor G2

Experimental hut trials and cluster-randomized clinical trials demonstrated the superior efficacy of dual-active ingredient nets combining pyrethroids with chlorfenapyr (a novel pyrrole uncoupler of oxidative phosphorylation with no cross-resistance).

> 90%Hut mortality
-44%Child malaria incidence
3 yrsValidated durability
04Operational Infrastructure

Field Stations & Experimental Huts

World-class trial network in Benin (Covè, Akron, CREC Cotonou)

OECD/WHO GLP compliant infrastructure enabling rigorous Phase II semi-field evaluations: flight tunnels, climate-controlled insectaries maintaining reference Kisumu strains, and high-throughput PCR genotyping platforms.

120Sentinel huts
45,000+Mosquitoes tested/yr
12Districts covered
05Partnerships & Network

International Collaboration Ecosystem

Academic synergies and global agencies

Close, continuous partnerships with the Entomological Research Center of Cotonou (CREC), London School of Hygiene & Tropical Medicine (LSHTM), PAMCA, WHO / TDR, The Global Fund, USAID / PMI, and University of Abomey-Calavi (UAC).

LSHTMUK Academic Partner
PAMCAPan-African Network
WHO / OMSGlobal Guidelines
06Conclusion & Contact

Towards Sustainable Malaria Elimination

Collaboration, operational research & mentorship

Available for keynote lectures, technical advisory committees, national program evaluations, and translational research consortia.

🌐idelphonseahogni.com
📍Cotonou, Republic of Benin